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Target Snapshot

CHEMBL363 Target Snapshot

Aspergillus fumigatus · ORGANISM · Aspergillus fumigatus

10,699Compounds
2,340Assays
8Approved Drugs
581.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Aspergillus fumigatus as ChEMBL target CHEMBL363. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Aspergillus fumigatus
ORGANISM · Aspergillus fumigatus
As of 2026-09-14
ChEMBL target ID
CHEMBL363
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Aspergillus fumigatus still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelAspergillus fumigatus
UniProt AccessionN/A

Aspergillus fumigatus

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Aspergillus fumigatus.

Review nameAspergillus fumigatus
OrganismAspergillus fumigatus
Clinical Profile

Clinical Phase Distribution

8
Approved
Assay Mix

Activity Type Distribution

IC50570.0
EC5011.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL267345 9.0 IC50 1.0 Approved
CHEMBL3577069 8.21 IC50 6.2 Preclinical
CHEMBL1630575 7.48 IC50 33.0 Approved
CHEMBL507425 6.07 IC50 860.0 Preclinical
CHEMBL443191 6.05 IC50 900.0 Preclinical
CHEMBL822 6.0 IC50 1000.0 Approved
CHEMBL454322 5.96 IC50 1100.0 Preclinical
CHEMBL522168 5.96 IC50 1100.0 Preclinical
CHEMBL70927 5.89 IC50 1290.0 Approved
CHEMBL574520 5.82 IC50 1500.0 Preclinical
Distribution

pChEMBL Value Distribution

23
5.0
18
5.5
6
6.0
2
6.5
1
7.0
0
7.5
1
8.0
0
8.5
1
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

CASPOFUNGIN
CHEMBL1630575
Approved 2001
TERBINAFINE
CHEMBL822
Approved 1992
AMPHOTERICIN B
CHEMBL267345
Approved 1964
Assay Landscape

Assay Landscape

2,345
Total Assays
68
Tested Compounds
2
Assay Types
Functional — 2,342 assays, 68 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 2,305 68 5.3
assay format 37 0
ADME — 3 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 2 0
organism-based format 1 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine