Compound Detail
CHEMBL507425
GEOMYCIN B Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
COC(=O)c1cc(OC(=O)c2c(O)cc(C)cc2Oc2c(OC)cc(O)cc2C(=O)OC)cc(OC)c1Oc1cc(C)cc(O)c1C(=O)O
Basic Information
| ChEMBL ID | CHEMBL507425 |
| Name | GEOMYCIN B |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZHHOOIJQRTVLKW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
678.6
MW (Da)
5.51
ALogP
14
HBA
4
HBD
213.8
PSA (Ų)
0.11
QED
3
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Aspergillus fumigatus CHEMBL363 | IC50 | 6.07 | 6.07 | 860.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Aspergillus fumigatus | IC50 | = | 860.0 | nM | 6.07 | Antifungal activity against Aspergillus fumigatus ATCC 10894 | 18720971 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18720971 | 10.1021/np8003003 | Aspergillus fumigatus | 2 |
Data from ChEMBL 36 via Core Engine