Assay Detail
Binding
CHEMBL1670079
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Binding affinity to human galectin-8 component 1 by surface plasmon resonance method
12
Total Activities
3
Compounds Tested
3
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and galectin-binding activities of mercaptododecyl glycosides containing a terminal β-galactosyl group.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 6 | 8.62 | 9.64 |
| Ka | 3 | - | - |
| Kdiss | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1669631 | — | — | 4 | 9.64 |
| CHEMBL1669628 | — | — | 4 | 8.81 |
| CHEMBL1669630 | — | — | 4 | 7.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1669631 | — | Kd | = | 0.23 | nM | 9.64 |
| CHEMBL1669631 | — | Kd | = | 0.233 | nM | 9.63 |
| CHEMBL1669628 | — | Kd | = | 1.55 | nM | 8.81 |
| CHEMBL1669628 | — | Kd | = | 1.6 | nM | 8.80 |
| CHEMBL1669630 | — | Kd | = | 37.0 | nM | 7.43 |
| CHEMBL1669630 | — | Kd | = | 36.9 | nM | 7.43 |
| CHEMBL1669628 | — | Ka | = | 8970.0 | 1/M.sec | - |
| CHEMBL1669630 | — | Ka | = | 18600.0 | 1/M.sec | - |
| CHEMBL1669631 | — | Ka | = | 9370.0 | 1/M.sec | - |
| CHEMBL1669628 | — | Kdiss | = | 1.39 | 10'-5/s | - |
| CHEMBL1669630 | — | Kdiss | = | 6.85 | 10'-2/s | - |
| CHEMBL1669631 | — | Kdiss | = | 2.18 | 10'-6/s | - |