Assay Detail
Binding
CHEMBL1670752
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Inhibition of IDO
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Indol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.42 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL275224 | NORHARMANE | — | 1 | 6.92 |
| CHEMBL373777 | BRASSININ | — | 1 | 4.92 |
| CHEMBL504816 | (L)-1-METHYLTRYPTOPHAN | — | 1 | 4.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL275224 | NORHARMANE | Ki | = | 120.0 | nM | 6.92 |
| CHEMBL373777 | BRASSININ | Ki | = | 12000.0 | nM | 4.92 |
| CHEMBL504816 | (L)-1-METHYLTRYPTOPHAN | Ki | = | 37000.0 | nM | 4.43 |