Assay Detail
Functional
CHEMBL1671398
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Antibacterial activity against Streptococcus pneumoniae CGMCC 1.1692 after 24 hrs
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Streptococcus pneumoniae |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
N-hydroxypyridones, phenylhydrazones, and a quinazolinone from Isaria farinosa.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.78 | 5.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL174 | AMPICILLIN | 4.0 | 1 | 5.97 |
| CHEMBL476496 | MILITARINONE B | — | 1 | 5.58 |
| CHEMBL1669191 | MILITARINONE E | — | 1 | - |
| CHEMBL1669192 | MILITARINONE F | — | 1 | - |
| CHEMBL1669193 | FARYLHYDRAZONE A | — | 1 | - |
| CHEMBL1669194 | FARYLHYDRAZONE B | — | 1 | - |
| CHEMBL1669195 | — | — | 1 | - |
| CHEMBL1669196 | MILITARINONE A | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL174 | AMPICILLIN | IC50 | = | 1080.0 | nM | 5.97 |
| CHEMBL476496 | MILITARINONE B | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL1669191 | MILITARINONE E | IC50 | > | 150000.0 | nM | - |
| CHEMBL1669192 | MILITARINONE F | IC50 | > | 150000.0 | nM | - |
| CHEMBL1669193 | FARYLHYDRAZONE A | IC50 | > | 150000.0 | nM | - |
| CHEMBL1669194 | FARYLHYDRAZONE B | IC50 | > | 150000.0 | nM | - |
| CHEMBL1669195 | — | IC50 | > | 150000.0 | nM | - |
| CHEMBL1669196 | MILITARINONE A | IC50 | > | 150000.0 | nM | - |