Assay Detail
Binding
CHEMBL1673910
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of pig kidney microsomal aminopeptidase N
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Chemical target validation studies of aminopeptidase in malaria parasites using alpha-aminoalkylphosphonate and phosphonopeptide inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 4.60 | 5.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1673065 | — | — | 1 | 5.43 |
| CHEMBL1090914 | — | — | 1 | 4.80 |
| CHEMBL1673064 | — | — | 1 | 4.43 |
| CHEMBL1673060 | — | — | 1 | 4.38 |
| CHEMBL288165 | — | — | 1 | 4.28 |
| CHEMBL1673062 | — | — | 1 | 4.26 |
| CHEMBL1673067 | — | — | 1 | - |
| CHEMBL1673081 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1673065 | — | Ki | = | 3690.0 | nM | 5.43 |
| CHEMBL1090914 | — | Ki | = | 15900.0 | nM | 4.80 |
| CHEMBL1673064 | — | Ki | = | 37100.0 | nM | 4.43 |
| CHEMBL1673060 | — | Ki | = | 41600.0 | nM | 4.38 |
| CHEMBL288165 | — | Ki | = | 53000.0 | nM | 4.28 |
| CHEMBL1673062 | — | Ki | = | 54700.0 | nM | 4.26 |
| CHEMBL1673067 | — | Ki | = | 161000.0 | nM | - |
| CHEMBL1673081 | — | Ki | > | 2000000.0 | nM | - |