Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1676101

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of APT1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Acyl-protein thioesterase 1 (CHEMBL1681631)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Small molecule inhibition of protein depalmitoylation as a new approach towards downregulation of oncogenic Ras signalling.
Dekker FJ, Hedberg C.
Bioorg Med Chem (2011) 19 : 1376 -1380
PubMed 21129981 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.17 6.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1673415 PALMOSTATIN B 1 6.17

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1673415 PALMOSTATIN B IC50 = 670.0 nM 6.17