Assay Detail
Binding
CHEMBL1679228
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Inhibition of recombinant VHR expressed in Escherichia coli
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Dual specificity protein phosphatase 3 (CHEMBL2635) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Inhibition of the Hematopoietic Protein Tyrosine Phosphatase by Phenoxyacetic Acids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.08 | 5.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1672292 | — | — | 1 | 5.38 |
| CHEMBL1672294 | — | — | 1 | 5.19 |
| CHEMBL1672293 | — | — | 1 | 5.07 |
| CHEMBL1672295 | — | — | 1 | 5.05 |
| CHEMBL1672291 | — | — | 1 | 4.71 |
| CHEMBL1672296 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1672292 | — | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL1672294 | — | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL1672293 | — | IC50 | = | 8500.0 | nM | 5.07 |
| CHEMBL1672295 | — | IC50 | = | 8900.0 | nM | 5.05 |
| CHEMBL1672291 | — | IC50 | = | 19500.0 | nM | 4.71 |
| CHEMBL1672296 | — | IC50 | > | 50000.0 | nM | - |