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Assay Detail

CHEMBL1679238

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Binding
Competitive inhibition of recombinant HePTP expressed in Escherichia coli by Michaelis-Menten kinetic analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Tyrosine-protein phosphatase non-receptor type 7 (CHEMBL2219)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Inhibition of the Hematopoietic Protein Tyrosine Phosphatase by Phenoxyacetic Acids.
Bobkova EV, Liu WH, Colayco S, Rascon J, Vasile S, Gasior C, Critton DA, Chan X, Dahl R, Su Y, Sergienko E, Chung TD, Mustelin T, Page R, Tautz L.
ACS Med Chem Lett (2011) 2 : 113 -118
PubMed 21503265 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.16 6.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1672291 1 6.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1672291 Ki = 690.0 nM 6.16