Assay Detail
Functional
CHEMBL1679740
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at androgen receptor expressed in mouse C2C12 cells assessed as osteoblast differentiation after 5 days
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | C2C12 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 10.15 | 10.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL27769 | STANOLONE | 2.0 | 1 | 10.30 |
| CHEMBL1672635 | RAD-140 | 2.0 | 1 | 10.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL27769 | STANOLONE | EC50 | = | 0.05 | nM | 10.30 |
| CHEMBL1672635 | RAD-140 | EC50 | = | 0.1 | nM | 10.00 |