Assay Detail
Functional
CHEMBL1685988
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Induction of lipolysis in mouse C3H10T1/2 assessed as glycerol concentration
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | C3H 10T1/2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of new inhibitor for PDE3 by virtual screening.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 8.05 | 8.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1683808 | — | — | 1 | 8.28 |
| CHEMBL1683805 | — | — | 1 | 8.17 |
| CHEMBL1683806 | — | — | 1 | 8.05 |
| CHEMBL34431 | CILOSTAMIDE | 2.0 | 1 | 8.04 |
| CHEMBL434 | ISOPROTERENOL | 4.0 | 1 | 7.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1683808 | — | EC50 | = | 5.2 | nM | 8.28 |
| CHEMBL1683805 | — | EC50 | = | 6.8 | nM | 8.17 |
| CHEMBL1683806 | — | EC50 | = | 8.9 | nM | 8.05 |
| CHEMBL34431 | CILOSTAMIDE | EC50 | = | 9.1 | nM | 8.04 |
| CHEMBL434 | ISOPROTERENOL | EC50 | = | 19.0 | nM | 7.72 |