Compound Detail
CHEMBL1683805
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Basic Information
| ChEMBL ID | CHEMBL1683805 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZJRQKCXAEUXDPY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
322.3
MW (Da)
2.02
ALogP
4
HBA
1
HBD
70.0
PSA (Ų)
0.91
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 8.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| C3H 10T1/2 CHEMBL614531 | EC50 | 8.17 | 8.17 | 6.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| C3H 10T1/2 | EC50 | = | 6.8 | nM | 8.17 | Induction of lipolysis in mouse C3H10T1/2 assessed as glycerol concentration | 21330134 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21330134 | 10.1016/j.bmcl.2011.01.120 | C3H 10T1/2 | 2 |
| 21330134 | 10.1016/j.bmcl.2011.01.120 | Adipocyte | 1 |
Data from ChEMBL 36 via Core Engine