Assay Detail
Functional
CHEMBL1686437
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Antiproliferative activity against human KPL4 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KPL4 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery and biological activity of a novel class I PI3K inhibitor, CH5132799.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.22 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1684986 | — | — | 1 | 7.82 |
| CHEMBL1684984 | IZORLISIB | 2.0 | 1 | 7.50 |
| CHEMBL1684985 | — | — | 1 | 6.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1684986 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL1684984 | IZORLISIB | IC50 | = | 32.0 | nM | 7.50 |
| CHEMBL1684985 | — | IC50 | = | 450.0 | nM | 6.35 |