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Assay Detail

CHEMBL1686955

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against HIV1 98IN022-C infected in human PBMC assessed as reduction of p24 antigen production after 7 days
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 1
Confidence 1 — Organism
Curated By Autocuration

Target

Human immunodeficiency virus 1 (CHEMBL378)
Type ORGANISM
Organism Human immunodeficiency virus 1

Publication

Novel potent pyrimido[4,5-c]quinoline inhibitors of protein kinase CK2: SAR and preliminary assessment of their analgesic and anti-viral properties.
Pierre F, O'Brien SE, Haddach M, Bourbon P, Schwaebe MK, Stefan E, Darjania L, Stansfield R, Ho C, Siddiqui-Jain A, Streiner N, Rice WG, Anderes K, Ryckman DM.
Bioorg Med Chem Lett (2011) 21 : 1687 -1691
PubMed 21316963 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.70 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1682297 1 6.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1682297 IC50 = 200.0 nM 6.70