Assay Detail
ADMET
CHEMBL1695398
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Cytotoxicity against rat L6 cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Rattus norvegicus |
| Cell Type | L6 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Compounds structurally related to ellagic acid show improved antiplasmodial activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.36 | 4.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1688543 | FLAVELLAGIC ACID | — | 1 | 4.68 |
| CHEMBL1688544 | CORULEOELLAGIC ACID | — | 1 | 4.03 |
| CHEMBL61 | PODOFILOX | 4.0 | 1 | - |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | - |
| CHEMBL6246 | ELLAGIC ACID | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1688543 | FLAVELLAGIC ACID | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL1688544 | CORULEOELLAGIC ACID | IC50 | = | 94000.0 | nM | 4.03 |
| CHEMBL61 | PODOFILOX | IC50 | = | 0.008 | ug.mL-1 | - |
| CHEMBL76 | CHLOROQUINE | IC50 | - | — | - | |
| CHEMBL6246 | ELLAGIC ACID | IC50 | - | — | - |