Assay Detail
Functional
CHEMBL1695409
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human GEO cells expressing IR assessed as intracellular ATP content after 3 days by Cell Titre-Glo luminescent assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | GEO |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of an Orally Efficacious Imidazo[5,1-f][1,2,4]triazine Dual Inhibitor of IGF-1R and IR.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.89 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1667935 | — | — | 1 | 6.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1667935 | — | EC50 | = | 130.0 | nM | 6.89 |