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Assay Detail

CHEMBL1696290

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Binding
Inhibition of cyclosporin binding to Cyp40 by fluorescence polarization competition assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Peptidyl-prolyl cis-trans isomerase D (CHEMBL1697657)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Facile synthesis of a fluorescent cyclosporin a analogue to study cyclophilin 40 and cyclophilin 18 ligands.
Gaali S, Kozany C, Hoogeland B, Klein M, Hausch F.
ACS Med Chem Lett (2010) 1 : 536 -539
PubMed 24900244 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 7.00 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1688203 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1688203 Kd = 101.0 nM 7.00