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Assay Detail

CHEMBL1738314

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: SAR Analysis of Selective Antagonists of GPR55 using an Image-Based Assay - Set 3. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2058, AID2079]
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Category confirmatory
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

G-protein coupled receptor 55 (CHEMBL1075322)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 14 4.96 5.18

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1720530 1 5.18
CHEMBL1708510 1 5.04
CHEMBL1709028 1 4.82
CHEMBL1727267 1 4.79
CHEMBL1718866 1 -
CHEMBL1709632 1 -
CHEMBL1700099 1 -
CHEMBL1700467 1 -
CHEMBL1701030 1 -
CHEMBL1723238 1 -
CHEMBL1723578 1 -
CHEMBL1704074 1 -
CHEMBL1734603 1 -
CHEMBL1716874 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1720530 IC50 = 6580.0 nM 5.18
CHEMBL1708510 IC50 = 9080.0 nM 5.04
CHEMBL1709028 IC50 = 15100.0 nM 4.82
CHEMBL1727267 IC50 = 16400.0 nM 4.79
CHEMBL1718866 IC50 > 32000.0 nM -
CHEMBL1709632 IC50 > 32000.0 nM -
CHEMBL1700099 IC50 > 32000.0 nM -
CHEMBL1700467 IC50 > 32000.0 nM -
CHEMBL1701030 IC50 > 32000.0 nM -
CHEMBL1723238 IC50 > 32000.0 nM -
CHEMBL1723578 IC50 > 32000.0 nM -
CHEMBL1704074 IC50 > 32000.0 nM -
CHEMBL1734603 IC50 > 32000.0 nM -
CHEMBL1716874 IC50 > 32000.0 nM -