Assay Detail
ADMET
CHEMBL1743486
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Mechanism based inhibition of human cytochrome P450 3A5 using expressed CYP3A5 cDNA
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 5.34 | 5.34 |
| Kinact | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1298 | NORVERAPAMIL | — | 2 | 5.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1298 | NORVERAPAMIL | Ki | = | 4530.0 | nM | 5.34 |
| CHEMBL1298 | NORVERAPAMIL | Kinact | = | 0.07 | min-1 | - |