Assay Detail
Binding
CHEMBL1763042
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Binding affinity to rat NK3 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of 3-aryl-5-acylpiperazinyl-pyrazoles as antagonists to the NK3 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.64 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1760338 | — | — | 1 | 6.60 |
| CHEMBL1760339 | — | — | 1 | 5.40 |
| CHEMBL1760200 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1760338 | — | Ki | = | 250.0 | nM | 6.60 |
| CHEMBL1760339 | — | Ki | = | 4000.0 | nM | 5.40 |
| CHEMBL1760200 | — | Ki | = | 12000.0 | nM | 4.92 |