Assay Detail
Binding
CHEMBL1763750
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Inhibition of FAAH in human T84 cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation counting
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | T84 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of potent, noncovalent fatty acid amide hydrolase (FAAH) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.85 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1761302 | — | — | 1 | 8.70 |
| CHEMBL1761301 | — | — | 1 | 8.52 |
| CHEMBL1761304 | — | — | 1 | 7.70 |
| CHEMBL1761300 | — | — | 1 | 6.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1761302 | — | EC50 | = | 2.0 | nM | 8.70 |
| CHEMBL1761301 | — | EC50 | = | 3.0 | nM | 8.52 |
| CHEMBL1761304 | — | EC50 | = | 20.0 | nM | 7.70 |
| CHEMBL1761300 | — | EC50 | = | 350.0 | nM | 6.46 |