Assay Detail
Binding
CHEMBL1764166
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Inhibition of Tyrosinase
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of bibenzyl glycosides as potent tyrosinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.03 | 6.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL499124 | — | — | 1 | 6.43 |
| CHEMBL491410 | — | — | 1 | 6.37 |
| CHEMBL1760463 | — | — | 1 | 6.17 |
| CHEMBL489989 | — | — | 1 | 6.14 |
| CHEMBL1760462 | — | — | 1 | 6.11 |
| CHEMBL1760464 | — | — | 1 | 6.08 |
| CHEMBL491409 | — | — | 1 | 5.80 |
| CHEMBL287556 | KOJIC ACID | — | 1 | 5.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL499124 | — | IC50 | = | 370.0 | nM | 6.43 |
| CHEMBL491410 | — | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL1760463 | — | IC50 | = | 680.0 | nM | 6.17 |
| CHEMBL489989 | — | IC50 | = | 730.0 | nM | 6.14 |
| CHEMBL1760462 | — | IC50 | = | 770.0 | nM | 6.11 |
| CHEMBL1760464 | — | IC50 | = | 830.0 | nM | 6.08 |
| CHEMBL491409 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL287556 | KOJIC ACID | IC50 | = | 7400.0 | nM | 5.13 |