Assay Detail

CHEMBL1764245

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Induction of intracellular calcium level in indo-1-labeled human neutrophils cells assessed as calcium mobilization

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

Neutrophil (CHEMBL613710) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

Neutrophil (CHEMBL613710) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Neutrophil

CHEMBL613710

Anchored from Assay target.

Protein identity Neutrophil

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	Neutrophil
Confidence	1 — Organism
Curated By	Autocuration

Target

Neutrophil (CHEMBL613710) ↗

Type

CELL-LINE

Publication

C20-trifluoro-5-oxo-ETE: a metabolically stable 5-oxo-ETE derivative.

Patel P, Gore V, Powell WS, Rokach J.
Bioorg Med Chem Lett (2011) 21 : 1987 -1990
PubMed 21377873 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	8.40	8.40

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL18028	5-OXO-ETE	—	1	8.40

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL18028	5-OXO-ETE	EC50	=	4.0	nM	8.40