Assay Detail
Binding
CHEMBL1767948
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Inhibition of human Cdc25B
8
Total Activities
8
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Using small molecules to target protein phosphatases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.67 | 6.90 |
| Ki | 1 | 7.02 | 7.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL337173 | — | — | 1 | 7.02 |
| CHEMBL429095 | — | — | 1 | 6.90 |
| CHEMBL1765351 | — | — | 1 | 6.60 |
| CHEMBL1765356 | — | — | 1 | 5.72 |
| CHEMBL459929 | — | — | 1 | 5.70 |
| CHEMBL228419 | — | — | 1 | 5.44 |
| CHEMBL1165659 | — | — | 1 | 5.00 |
| CHEMBL1765352 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL337173 | — | Ki | = | 95.0 | nM | 7.02 |
| CHEMBL429095 | — | IC50 | = | 125.0 | nM | 6.90 |
| CHEMBL1765351 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL1765356 | — | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL459929 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL228419 | — | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL1165659 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1765352 | — | IC50 | = | 50000.0 | nM | 4.30 |