Assay Detail
Binding
CHEMBL1767949
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Inhibition of human Cdc25C
6
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Using small molecules to target protein phosphatases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.62 | 7.25 |
| Ki | 1 | 7.05 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL429095 | — | — | 1 | 7.25 |
| CHEMBL337173 | — | — | 1 | 7.05 |
| CHEMBL1765351 | — | — | 1 | 6.77 |
| CHEMBL228419 | — | — | 1 | 5.37 |
| CHEMBL1165659 | — | — | 1 | 4.40 |
| CHEMBL1765352 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL429095 | — | IC50 | = | 56.9 | nM | 7.25 |
| CHEMBL337173 | — | Ki | = | 89.0 | nM | 7.05 |
| CHEMBL1765351 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL228419 | — | IC50 | = | 4300.0 | nM | 5.37 |
| CHEMBL1165659 | — | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL1765352 | — | IC50 | = | 50000.0 | nM | 4.30 |