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Assay Detail

CHEMBL1768069

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Mycobacterium tuberculosis ptpA
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mycobacterium tuberculosis
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Low molecular weight protein-tyrosine phosphatase A (CHEMBL4542)
Type SINGLE PROTEIN
Organism Mycobacterium tuberculosis

Publication

Using small molecules to target protein phosphatases.
Vintonyak VV, Waldmann H, Rauh D.
Bioorg Med Chem (2011) 19 : 2145 -2155
PubMed 21420867 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.05 6.05
Ki 1 5.80 5.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1765359 1 6.05
CHEMBL1765360 1 5.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1765359 IC50 = 900.0 nM 6.05
CHEMBL1765360 Ki = 1600.0 nM 5.80