Assay Detail
Functional
CHEMBL1769980
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Cytotoxicity against human JMAR cells assessed as cell viability by MTS assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | JMAR |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic oleanane-type saponins from Albizia inundata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.14 | 5.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1765595 | — | — | 1 | 5.55 |
| CHEMBL1765593 | — | — | 1 | 5.06 |
| CHEMBL1765596 | PITHEDULOSIDE C | — | 1 | 5.00 |
| CHEMBL1765597 | — | — | 1 | 4.94 |
| CHEMBL1765594 | — | — | 1 | - |
| CHEMBL509569 | PROSAPOGENIN 4 | — | 1 | - |
| CHEMBL504527 | ACUTOSIDE A | — | 1 | - |
| CHEMBL1765591 | — | — | 1 | - |
| CHEMBL1765592 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1765595 | — | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL1765593 | — | IC50 | = | 8700.0 | nM | 5.06 |
| CHEMBL1765596 | PITHEDULOSIDE C | IC50 | = | 10100.0 | nM | 5.00 |
| CHEMBL1765597 | — | IC50 | = | 11500.0 | nM | 4.94 |
| CHEMBL1765594 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL509569 | PROSAPOGENIN 4 | IC50 | > | 20000.0 | nM | - |
| CHEMBL504527 | ACUTOSIDE A | IC50 | > | 20000.0 | nM | - |
| CHEMBL1765591 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL1765592 | — | IC50 | > | 20000.0 | nM | - |