Assay Detail
ADMET
CHEMBL1775550
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Cytotoxicity against rat RAW264.7 cells by MTT assay
6
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Rattus norvegicus |
| Cell Type | RAW264.7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A chemotype that inhibits three unrelated pathogenic targets: the botulinum neurotoxin serotype A light chain, P. falciparum malaria, and the Ebola filovirus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.05 | 5.13 |
| IC90 | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1773165 | — | — | 2 | 5.13 |
| CHEMBL1773160 | — | — | 2 | 5.03 |
| CHEMBL1773073 | — | — | 2 | 4.99 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1773165 | — | IC50 | = | 7481.0 | nM | 5.13 |
| CHEMBL1773160 | — | IC50 | = | 9348.0 | nM | 5.03 |
| CHEMBL1773073 | — | IC50 | = | 10174.0 | nM | 4.99 |
| CHEMBL1773160 | — | IC90 | = | 10717.0 | nM | - |
| CHEMBL1773165 | — | IC90 | = | 11029.0 | nM | - |
| CHEMBL1773073 | — | IC90 | = | 29916.0 | nM | - |