Assay Detail
Functional
CHEMBL1775561
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Antiviral activity against Zaire ebolavirus expressing enhanced GFP in Vero 76 cells after 48 hrs by standard Plaque assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Zaire ebolavirus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A chemotype that inhibits three unrelated pathogenic targets: the botulinum neurotoxin serotype A light chain, P. falciparum malaria, and the Ebola filovirus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.40 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1773165 | — | — | 1 | 5.60 |
| CHEMBL1773160 | — | — | 1 | 5.30 |
| CHEMBL1773163 | — | — | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1773165 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL1773160 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL1773163 | — | IC50 | = | 5000.0 | nM | 5.30 |