Assay Detail
Binding
CHEMBL1780997
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rat 5-alpha-reductase type 2 by Lineweaver-Burk plot
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (CHEMBL5099) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Synthesis and bioactivity of new Finasteride conjugate.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.95 | 7.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1778071 | — | — | 1 | 7.06 |
| CHEMBL710 | FINASTERIDE | 4.0 | 1 | 6.83 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1778071 | — | IC50 | = | 87.98 | nM | 7.06 |
| CHEMBL710 | FINASTERIDE | IC50 | = | 147.49 | nM | 6.83 |