Assay Detail
Binding
CHEMBL1781797
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Inhibition of rat SGLT2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Optimization of triazoles as novel and potent nonphlorizin SGLT2 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.49 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1779345 | — | — | 1 | 8.52 |
| CHEMBL1779341 | — | — | 1 | 8.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1779345 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL1779341 | — | IC50 | = | 3.5 | nM | 8.46 |