Sodium/glucose cotransporter 2 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P53792. Use UniProt P53792 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P53792 as the stable identity anchor, then attach disease evidence before program review.
Sodium/glucose cotransporter 2
Review this target as Sodium/glucose cotransporter 2, mapped to UniProt P53792. Sequence length is 670 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sodium/glucose cotransporter 2 as ChEMBL target CHEMBL4316, mapped to UniProt P53792. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sodium/glucose cotransporter 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P53792 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sodium/glucose cotransporter 2 |
| UniProt Accession | P53792 |
| Component Type | Protein |
| Sequence Length | 670 aa |
Sodium/glucose cotransporter 2
Review this target as Sodium/glucose cotransporter 2, mapped to UniProt P53792. Sequence length is 670 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1770248 | 8.94 | IC50 | 1.15 | Approved |
| CHEMBL429910 | 8.52 | EC50 | 3.0 | Approved |
| CHEMBL1779345 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL1779341 | 8.46 | IC50 | 3.5 | Preclinical |
| CHEMBL4279519 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL245067 | 7.02 | IC50 | 96.0 | Preclinical |
| CHEMBL3818220 | 6.7 | Kd | 200.0 | Preclinical |
| CHEMBL1762483 | 6.4 | IC50 | 400.0 | Preclinical |
| CHEMBL2323695 | 5.94 | IC50 | 1160.0 | Preclinical |
| CHEMBL2323694 | 5.37 | IC50 | 4280.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 8 | 6.1 |
| single protein format | 4 | 7 | 7.3 |
| assay format | 1 | 1 | 6.7 |