Assay Detail
Binding
CHEMBL1781813
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human Oat1 expressed in Drosophila S2 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | S2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Solute carrier family 22 member 6 (CHEMBL1641347) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter-Organic anion transporter1 (Oat1).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 4.93 | 5.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL463 | AMINOHIPPURIC ACID | 4.0 | 1 | 5.22 |
| CHEMBL1231530 | BETAMIPRON | 2.0 | 1 | 4.63 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL463 | AMINOHIPPURIC ACID | Ki | = | 6020.0 | nM | 5.22 |
| CHEMBL1231530 | BETAMIPRON | Ki | = | 23600.0 | nM | 4.63 |