Assay Detail
Binding
CHEMBL1785512
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of COX2-mediated PGE2 production in LPS-induced mouse MC3T3-E1 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | MC3T3-E1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Hop (Humulus lupulus)-derived bitter acids as multipotent bioactive compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.52 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL512227 | HUMULONE | — | 1 | 7.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL512227 | HUMULONE | IC50 | = | 30.0 | nM | 7.52 |