Prostaglandin G/H synthase 2 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q05769. Use UniProt Q05769 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q05769 as the stable identity anchor, then attach disease evidence before program review.
Prostaglandin G/H synthase 2
Review this target as Prostaglandin G/H synthase 2, mapped to UniProt Q05769. Sequence length is 604 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Prostaglandin G/H synthase 2 as ChEMBL target CHEMBL4321, mapped to UniProt Q05769. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Prostaglandin G/H synthase 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q05769 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Prostaglandin G/H synthase 2 |
| UniProt Accession | Q05769 |
| Component Type | Protein |
| Sequence Length | 604 aa |
Prostaglandin G/H synthase 2
Review this target as Prostaglandin G/H synthase 2, mapped to UniProt Q05769. Sequence length is 604 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL499069 | 10.7 | IC50 | 0.01995 | Preclinical |
| CHEMBL501208 | 10.7 | IC50 | 0.01995 | Preclinical |
| CHEMBL525247 | 10.7 | IC50 | 0.01995 | Preclinical |
| CHEMBL502555 | 10.16 | IC50 | 0.06918 | Preclinical |
| CHEMBL500936 | 10.05 | IC50 | 0.08913 | Preclinical |
| CHEMBL524543 | 10.05 | IC50 | 0.08913 | Preclinical |
| CHEMBL499349 | 9.85 | IC50 | 0.1413 | Preclinical |
| CHEMBL525021 | 9.77 | IC50 | 0.1698 | Preclinical |
| CHEMBL500943 | 9.75 | IC50 | 0.1778 | Preclinical |
| CHEMBL525250 | 9.55 | IC50 | 0.2818 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 96 | 327 | 7.0 |
| cell-based format | 78 | 252 | 6.5 |
| assay format | 11 | 53 | 6.7 |
| tissue-based format | 2 | 3 | 4.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 4 | 8.7 |
| organism-based format | 2 | 4 | 7.6 |
| cell-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 0 | — |