Assay Detail
Binding
CHEMBL1785589
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]estradiol from human full-length ERbeta receptor by competitive radiometric binding assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Selective and potent agonists for estrogen receptor beta derived from molecular refinements of salicylaldoximes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.33 | 9.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1782957 | — | — | 1 | 9.42 |
| CHEMBL1782958 | — | — | 1 | 9.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1782957 | — | Ki | = | 0.38 | nM | 9.42 |
| CHEMBL1782958 | — | Ki | = | 0.57 | nM | 9.24 |