Assay Detail
Binding
CHEMBL1785600
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of fluorescent 1-anilinonapthalene 8-sulfonic acid from human a-FABP by fluorescence spectrophotometry
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Fatty acid-binding protein, adipocyte (CHEMBL2083) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 7.98 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1782966 | — | — | 1 | 8.30 |
| CHEMBL1782968 | — | — | 1 | 8.22 |
| CHEMBL1782965 | — | — | 1 | 8.15 |
| CHEMBL1782964 | — | — | 1 | 7.89 |
| CHEMBL247920 | — | — | 1 | 7.82 |
| CHEMBL1782963 | — | — | 1 | 7.50 |
| CHEMBL1782967 | — | — | 1 | - |
| CHEMBL1782969 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1782966 | — | Ki | = | 5.0 | nM | 8.30 |
| CHEMBL1782968 | — | Ki | = | 6.0 | nM | 8.22 |
| CHEMBL1782965 | — | Ki | = | 7.0 | nM | 8.15 |
| CHEMBL1782964 | — | Ki | = | 13.0 | nM | 7.89 |
| CHEMBL247920 | — | Ki | = | 15.0 | nM | 7.82 |
| CHEMBL1782963 | — | Ki | = | 32.0 | nM | 7.50 |
| CHEMBL1782967 | — | Ki | < | 1.0 | nM | - |
| CHEMBL1782969 | — | Ki | < | 1.0 | nM | - |