Assay Detail

CHEMBL1785653

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Functional

Antioxidant activity assessed as inhibition of lipid peroxidation

ChEMBL ↗

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Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

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Primary target NON-PROTEIN TARGET

CHEMBL3879801

Anchored from Assay target.

Protein identity NON-PROTEIN TARGET

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Confidence	1 — Organism
Curated By	Autocuration

Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

Type	NON-MOLECULAR

Publication

Hop (Humulus lupulus)-derived bitter acids as multipotent bioactive compounds.

Van Cleemput M, Cattoor K, De Bosscher K, Haegeman G, De Keukeleire D, Heyerick A.
J Nat Prod (2009) 72 : 1220 -1230
PubMed 19476340 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	4.76	5.10

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL512227	HUMULONE	—	1	5.10
CHEMBL480267	LUPULONE	—	1	4.41

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL512227	HUMULONE	IC50	=	7900.0	nM	5.10
CHEMBL480267	LUPULONE	IC50	=	39000.0	nM	4.41