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Assay Detail

CHEMBL1787357

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Functional
Antiproliferative activity against human HeLaS3 cells after 72 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HeLa S3
Confidence 1 — Organism
Curated By Autocuration

Publication

Synthesis and biological evaluation of boron peptide analogues of Belactosin C as proteasome inhibitors.
Nakamura H, Watanabe M, Ban HS, Nabeyama W, Asai A.
Bioorg Med Chem Lett (2009) 19 : 3220 -3224
PubMed 19428245 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.29 4.29

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL491636 BELACTOSIN A 1 4.29
CHEMBL1783833 BELACTOSIN C 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL491636 BELACTOSIN A IC50 = 51000.0 nM 4.29
CHEMBL1783833 BELACTOSIN C IC50 = 200000.0 nM -