Assay Detail
Functional
CHEMBL1794366
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Dose response confirmation of uHTS hits for small molecule modulators of myocardial damage using 2-dexoy-glucose. (Class of assay: confirmatory)
1491
Total Activities
1491
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Tissue | Myocardium |
| Category | confirmatory |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1491 | 4.71 | 5.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1892448 | — | — | 1 | 5.28 |
| CHEMBL1563920 | — | — | 1 | 5.28 |
| CHEMBL1884334 | — | — | 1 | 5.28 |
| CHEMBL1319627 | — | — | 1 | 5.26 |
| CHEMBL1548173 | — | — | 1 | 5.24 |
| CHEMBL1550633 | — | — | 1 | 5.24 |
| CHEMBL1423858 | — | — | 1 | 5.24 |
| CHEMBL1467641 | — | — | 1 | 5.23 |
| CHEMBL1515432 | — | — | 1 | 5.22 |
| CHEMBL1712358 | — | — | 1 | 5.22 |
| CHEMBL1992883 | — | — | 1 | 5.21 |
| CHEMBL1867569 | — | — | 1 | 5.20 |
| CHEMBL1300649 | — | — | 1 | 5.18 |
| CHEMBL1544440 | — | — | 1 | 5.18 |
| CHEMBL1530972 | — | — | 1 | 5.17 |
| CHEMBL1303540 | — | — | 1 | 5.17 |
| CHEMBL1996360 | — | — | 1 | 5.16 |
| CHEMBL1474877 | — | — | 1 | 5.15 |
| CHEMBL1540513 | — | — | 1 | 5.14 |
| CHEMBL1328779 | — | — | 1 | 5.14 |
| CHEMBL1441149 | — | — | 1 | 5.13 |
| CHEMBL1882485 | — | — | 1 | 5.12 |
| CHEMBL1459757 | — | — | 1 | 5.12 |
| CHEMBL1495112 | — | — | 1 | 5.11 |
| CHEMBL1570792 | — | — | 1 | 5.11 |
| CHEMBL1365331 | — | — | 1 | 5.10 |
| CHEMBL1432015 | — | — | 1 | 5.09 |
| CHEMBL1495927 | — | — | 1 | 5.09 |
| CHEMBL1716393 | — | — | 1 | 5.09 |
| CHEMBL1972133 | — | — | 1 | 5.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1563920 | — | IC50 | = | 5305.0 | nM | 5.28 |
| CHEMBL1884334 | — | IC50 | = | 5282.0 | nM | 5.28 |
| CHEMBL1892448 | — | IC50 | = | 5223.0 | nM | 5.28 |
| CHEMBL1319627 | — | IC50 | = | 5510.0 | nM | 5.26 |
| CHEMBL1550633 | — | IC50 | = | 5732.0 | nM | 5.24 |
| CHEMBL1548173 | — | IC50 | = | 5762.0 | nM | 5.24 |
| CHEMBL1423858 | — | IC50 | = | 5782.0 | nM | 5.24 |
| CHEMBL1467641 | — | IC50 | = | 5880.0 | nM | 5.23 |
| CHEMBL1515432 | — | IC50 | = | 6028.0 | nM | 5.22 |
| CHEMBL1712358 | — | IC50 | = | 6015.0 | nM | 5.22 |
| CHEMBL1992883 | — | IC50 | = | 6206.0 | nM | 5.21 |
| CHEMBL1867569 | — | IC50 | = | 6389.0 | nM | 5.20 |
| CHEMBL1300649 | — | IC50 | = | 6569.0 | nM | 5.18 |
| CHEMBL1544440 | — | IC50 | = | 6544.0 | nM | 5.18 |
| CHEMBL1530972 | — | IC50 | = | 6832.0 | nM | 5.17 |
| CHEMBL1303540 | — | IC50 | = | 6810.0 | nM | 5.17 |
| CHEMBL1996360 | — | IC50 | = | 6881.0 | nM | 5.16 |
| CHEMBL1474877 | — | IC50 | = | 7047.0 | nM | 5.15 |
| CHEMBL1328779 | — | IC50 | = | 7233.0 | nM | 5.14 |
| CHEMBL1540513 | — | IC50 | = | 7200.0 | nM | 5.14 |
| CHEMBL1441149 | — | IC50 | = | 7332.0 | nM | 5.13 |
| CHEMBL1459757 | — | IC50 | = | 7591.0 | nM | 5.12 |
| CHEMBL1882485 | — | IC50 | = | 7563.0 | nM | 5.12 |
| CHEMBL1495112 | — | IC50 | = | 7770.0 | nM | 5.11 |
| CHEMBL1570792 | — | IC50 | = | 7705.0 | nM | 5.11 |
| CHEMBL1365331 | — | IC50 | = | 8018.0 | nM | 5.10 |
| CHEMBL1716393 | — | IC50 | = | 8057.0 | nM | 5.09 |
| CHEMBL1495927 | — | IC50 | = | 8047.0 | nM | 5.09 |
| CHEMBL1432015 | — | IC50 | = | 8164.0 | nM | 5.09 |
| CHEMBL1972133 | — | IC50 | = | 8375.0 | nM | 5.08 |
| CHEMBL1426855 | — | IC50 | = | 8509.0 | nM | 5.07 |
| CHEMBL1323071 | — | IC50 | = | 8474.0 | nM | 5.07 |
| CHEMBL1966961 | — | IC50 | = | 8807.0 | nM | 5.05 |
| CHEMBL1992977 | — | IC50 | = | 8874.0 | nM | 5.05 |
| CHEMBL1584950 | — | IC50 | = | 9071.0 | nM | 5.04 |
| CHEMBL1965758 | — | IC50 | = | 9020.0 | nM | 5.04 |
| CHEMBL1609946 | — | IC50 | = | 9063.0 | nM | 5.04 |
| CHEMBL1726644 | — | IC50 | = | 9058.0 | nM | 5.04 |
| CHEMBL1595051 | — | IC50 | = | 9063.0 | nM | 5.04 |
| CHEMBL1975051 | — | IC50 | = | 9137.0 | nM | 5.04 |
| CHEMBL1497333 | — | IC50 | = | 9137.0 | nM | 5.04 |
| CHEMBL1351484 | — | IC50 | = | 9437.0 | nM | 5.03 |
| CHEMBL1872607 | — | IC50 | = | 9397.0 | nM | 5.03 |
| CHEMBL1996299 | — | IC50 | = | 9301.0 | nM | 5.03 |
| CHEMBL1313763 | — | IC50 | = | 9433.0 | nM | 5.03 |
| CHEMBL1545864 | — | IC50 | = | 9320.0 | nM | 5.03 |
| CHEMBL1555499 | — | IC50 | = | 9582.0 | nM | 5.02 |
| CHEMBL1877015 | — | IC50 | = | 9615.0 | nM | 5.02 |
| CHEMBL1529402 | — | IC50 | = | 9563.0 | nM | 5.02 |
| CHEMBL1420497 | — | IC50 | = | 9667.0 | nM | 5.01 |