Compound Detail
CHEMBL1548173
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Basic Information
| ChEMBL ID | CHEMBL1548173 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LSFAWTODWZZGOF-SJORKVTESA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
379.2
MW (Da)
3.14
ALogP
5
HBA
1
HBD
65.0
PSA (Ų)
0.89
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.24
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.24 | 5.24 | 5762.0 | 1 |
| Type-1 angiotensin II receptor CHEMBL227 | IC50 | 4.46 | 4.46 | 34590.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 5762.0 | nM | 5.24 | PUBCHEM_BIOASSAY: Dose response confirmation of uHTS hits for small molecule mod... | - |
| Type-1 angiotensin II receptor | IC50 | = | 34590.0 | nM | 4.46 | PUBCHEM_BIOASSAY: Dose Response screen for antagonists of Angiotensin II Recepto... | - |
Data from ChEMBL 36 via Core Engine