Assay Detail
Binding
CHEMBL1803288
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Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK-293-EBNA cell membranes after 90 mins by scintillation counting
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | EBNA |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of endocannabinoid-based chemical probes for the study of cannabinoid receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 11 | 6.46 | 7.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1800732 | — | — | 1 | 7.07 |
| CHEMBL1800082 | — | — | 1 | 6.58 |
| CHEMBL1800730 | — | — | 1 | 6.42 |
| CHEMBL1800731 | — | — | 1 | 6.35 |
| CHEMBL122972 | 2-ARACHIDONOYLGLYCEROL | — | 1 | 5.89 |
| CHEMBL146346 | — | — | 1 | - |
| CHEMBL1800181 | — | — | 1 | - |
| CHEMBL1800182 | — | — | 1 | - |
| CHEMBL1800727 | — | — | 1 | - |
| CHEMBL1800728 | — | — | 1 | - |
| CHEMBL1800729 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1800732 | — | Ki | = | 84.9 | nM | 7.07 |
| CHEMBL1800082 | — | Ki | = | 260.0 | nM | 6.58 |
| CHEMBL1800730 | — | Ki | = | 379.0 | nM | 6.42 |
| CHEMBL1800731 | — | Ki | = | 450.0 | nM | 6.35 |
| CHEMBL122972 | 2-ARACHIDONOYLGLYCEROL | Ki | = | 1300.0 | nM | 5.89 |
| CHEMBL146346 | — | Ki | > | 1000.0 | nM | - |
| CHEMBL1800181 | — | Ki | > | 2000.0 | nM | - |
| CHEMBL1800182 | — | Ki | > | 2000.0 | nM | - |
| CHEMBL1800727 | — | Ki | > | 2000.0 | nM | - |
| CHEMBL1800728 | — | Ki | > | 2000.0 | nM | - |
| CHEMBL1800729 | — | Ki | > | 2000.0 | nM | - |