Assay Detail
Binding
CHEMBL1805658
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Binding affinity to ERalpha by fluorescence polarization assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Dimethyl-diphenyl-propanamide derivatives as nonsteroidal dissociated glucocorticoid receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 5.45 | 5.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1800984 | — | — | 1 | 5.64 |
| CHEMBL1800985 | — | — | 1 | 5.26 |
| CHEMBL131 | PREDNISOLONE | 4.0 | 1 | - |
| CHEMBL1801012 | — | — | 1 | - |
| CHEMBL1801008 | — | — | 1 | - |
| CHEMBL1801006 | — | — | 1 | - |
| CHEMBL1800981 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1800984 | — | Ki | = | 2300.0 | nM | 5.64 |
| CHEMBL1800985 | — | Ki | = | 5500.0 | nM | 5.26 |
| CHEMBL131 | PREDNISOLONE | Ki | > | 5000.0 | nM | - |
| CHEMBL1801012 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL1801008 | — | Ki | > | 50000.0 | nM | - |
| CHEMBL1801006 | — | Ki | > | 50000.0 | nM | - |
| CHEMBL1800981 | — | Ki | > | 50000.0 | nM | - |