Assay Detail
Binding
CHEMBL1805660
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Binding affinity to androgen receptor by fluorescence polarization assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Dimethyl-diphenyl-propanamide derivatives as nonsteroidal dissociated glucocorticoid receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 6.03 | 6.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1801006 | — | — | 1 | 6.43 |
| CHEMBL1800985 | — | — | 1 | 6.16 |
| CHEMBL1800981 | — | — | 1 | 6.00 |
| CHEMBL1801008 | — | — | 1 | 5.99 |
| CHEMBL1801012 | — | — | 1 | 5.98 |
| CHEMBL1800984 | — | — | 1 | 5.63 |
| CHEMBL1801005 | — | — | 1 | - |
| CHEMBL1800983 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1801006 | — | Ki | = | 370.0 | nM | 6.43 |
| CHEMBL1800985 | — | Ki | = | 696.0 | nM | 6.16 |
| CHEMBL1800981 | — | Ki | = | 993.0 | nM | 6.00 |
| CHEMBL1801008 | — | Ki | = | 1034.0 | nM | 5.99 |
| CHEMBL1801012 | — | Ki | = | 1058.0 | nM | 5.98 |
| CHEMBL1800984 | — | Ki | = | 2341.0 | nM | 5.63 |
| CHEMBL1801005 | — | Ki | > | 3000.0 | nM | - |
| CHEMBL1800983 | — | Ki | > | 4000.0 | nM | - |