Assay Detail
Functional
CHEMBL1806221
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at GFP tagged-human P2Y11 receptor expressed in human 1321N1 cells assessed as elevation in calcium level after 30 mins by fluorescence spectrophotometric analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | 1321-N1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Diadenosine 5',5''-(boranated)polyphosphonate analogues as selective nucleotide pyrophosphatase/phosphodiesterase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.19 | 5.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL14249 | ADENOSINE TRIPHOSPHATE | 2.0 | 1 | 5.48 |
| CHEMBL1802094 | — | — | 1 | 4.89 |
| CHEMBL1802096 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL14249 | ADENOSINE TRIPHOSPHATE | EC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL1802094 | — | EC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL1802096 | — | EC50 | >= | 40000.0 | nM | - |