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Assay Detail

CHEMBL1809455

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to PKCeta-C1B domain peptide using [3H]-labeled compound
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Protein kinase C eta type (CHEMBL3616)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Generation of 'Unnatural Natural Product' library and identification of a small molecule inhibitor of XIAP.
Kawamura T, Matsubara K, Otaka H, Tashiro E, Shindo K, Yanagita RC, Irie K, Imoto M.
Bioorg Med Chem (2011) 19 : 4377 -4385
PubMed 21696964 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 9.35 9.35

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL27768 1 9.35

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL27768 Kd = 0.45 nM 9.35