Assay Detail
ADMET
CHEMBL1811512
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Cytotoxicity against human HEK293T cells expressing AP-1 after 18 hrs by XTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HEK-293T |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Nothospondin, a new AP-1 inhibitory quassinoid from the Cameroonian plant Nothospondias staudtii.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.00 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1807644 | NOTHOSPONDIN | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1807644 | NOTHOSPONDIN | IC50 | = | 10000.0 | nM | 5.00 |