Assay Detail
Binding
CHEMBL1815363
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-SQ29548 from human TP receptor expressed in CHO cells after 30 mins by liquid scintillation counting
11
Total Activities
11
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of selective indole-based prostaglandin D₂ receptor antagonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.58 | 6.58 |
| IC50 | 4 | 5.12 | 5.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL364841 | — | — | 1 | 6.58 |
| CHEMBL1813287 | — | — | 1 | 5.12 |
| CHEMBL1813276 | — | — | 1 | - |
| CHEMBL6 | INDOMETHACIN | 4.0 | 1 | - |
| CHEMBL1813115 | — | — | 1 | - |
| CHEMBL1813116 | — | — | 1 | - |
| CHEMBL1813117 | — | — | 1 | - |
| CHEMBL1813118 | — | — | 1 | - |
| CHEMBL1813119 | — | — | 1 | - |
| CHEMBL1813120 | — | — | 1 | - |
| CHEMBL1813121 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL364841 | — | Ki | = | 260.0 | nM | 6.58 |
| CHEMBL1813287 | — | IC50 | = | 7600.0 | nM | 5.12 |
| CHEMBL1813276 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL6 | INDOMETHACIN | Ki | - | — | - | |
| CHEMBL1813115 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1813116 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1813117 | — | Ki | - | — | - | |
| CHEMBL1813118 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1813119 | — | Ki | - | — | - | |
| CHEMBL1813120 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL1813121 | — | IC50 | - | — | - |