Assay Detail
Binding
CHEMBL1816093
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Reversible inhibition of human FAAH
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The discovery and development of inhibitors of fatty acid amide hydrolase (FAAH).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 8.65 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1812715 | — | — | 1 | 9.00 |
| CHEMBL1812716 | — | — | 1 | 8.89 |
| CHEMBL1761455 | — | — | 1 | 8.70 |
| CHEMBL1761282 | — | — | 1 | 8.00 |
| CHEMBL1812713 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1812715 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL1812716 | — | IC50 | = | 1.3 | nM | 8.89 |
| CHEMBL1761455 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL1761282 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL1812713 | — | IC50 | < | 100.0 | nM | - |