Assay Detail
Binding
CHEMBL1816569
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant MAOA expressed in insect cells using kynuramine substrate by fluorescence spectroscopy
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibition of monoamine oxidase by C5-substituted phthalimide analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.72 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1813523 | — | — | 1 | 6.66 |
| CHEMBL1813522 | — | — | 1 | 6.04 |
| CHEMBL1813524 | — | — | 1 | 5.97 |
| CHEMBL1813525 | — | — | 1 | 5.97 |
| CHEMBL1813520 | — | — | 1 | 5.76 |
| CHEMBL1813519 | — | — | 1 | 5.45 |
| CHEMBL342357 | — | — | 1 | 5.38 |
| CHEMBL1813518 | — | — | 1 | 5.23 |
| CHEMBL1813521 | — | — | 1 | 5.05 |
| CHEMBL277294 | PHTHALIMIDE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1813523 | — | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL1813522 | — | IC50 | = | 920.0 | nM | 6.04 |
| CHEMBL1813524 | — | IC50 | = | 1080.0 | nM | 5.97 |
| CHEMBL1813525 | — | IC50 | = | 1080.0 | nM | 5.97 |
| CHEMBL1813520 | — | IC50 | = | 1730.0 | nM | 5.76 |
| CHEMBL1813519 | — | IC50 | = | 3580.0 | nM | 5.45 |
| CHEMBL342357 | — | IC50 | = | 4170.0 | nM | 5.38 |
| CHEMBL1813518 | — | IC50 | = | 5850.0 | nM | 5.23 |
| CHEMBL1813521 | — | IC50 | = | 8990.0 | nM | 5.05 |
| CHEMBL277294 | PHTHALIMIDE | IC50 | = | 165000.0 | nM | - |